ABSTRACT
Insulinoma is a type of functional pancreatic neuroendocrine neoplasms(p NENs).As symptoms of hypoglycemia due to hyperinsulinemia are varied and nonspecific,diagnosis of insulinoma tends to be quite difficult.Both of localization diagnosis and surgical management are key points to deal with insulinoma.As for localization,while traditional imaging methods like CT and MRI improve quite fast,new molecular imaging technologies also develop rapidly.In terms of surgical treatment,main concerns of physicians often focus on the evaluation of operative procedures and experience of operating points.
ABSTRACT
<p><b>OBJECTIVE</b>To explore feasibility of applying evidence grading system in clinical decision-making analysis.</p><p><b>METHODS</b>Using grading system as well as a quantitative approach to generate the threshold NNT((T)), and conducting clinical decision-making analysis through one study on Asymptomatic carotid atherosclerosis.</p><p><b>RESULTS</b>NNT((T)) was 12, comparing with no-intervention in the ACA study that NNT = 6. NNT < NNT((T)) indicated the benefits of intervention outweigh the risks and costs.</p><p><b>CONCLUSION</b>To obtain the rate of adverse event and the specifying approximate cost were vital in the process of applying grading system in clinical decision-making.</p>